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Archive (2015–2005)

Biomedical and Health Informatics in Translational Medicine

Journal: Methods of Information in Medicine
Subtitle: A journal stressing, for more than 50 years, the methodology and scientific fundamentals of organizing, representing and analyzing data, information and knowledge in biomedicine and health care
ISSN: 0026-1270
Issue: 2009 (Vol. 48): Issue 1 2009
Pages: 4-10

Biomedical and Health Informatics in Translational Medicine

C. A. Kulikowski (1), C. W. Kulikowski (1)

(1) Department of Computer Science, Rutgers University, New Brunswick, New Jersey, USA


Health Informatics, Medical Ethics, Decision-making, Healthcare, Translational medicine, semantic web, clinome, Translational bioinformatics, genome-phenome interactions, scaling, complex decisions


Objectives: To discuss translational medicine advances challenging biomedical and health informatics. Methods : Reviewing material presented at the Heidelberg 35th Anniversary Workshop, summarizing results from the 1st AMIA Summit on Translational Bioinformatics and discussing the opportunities, difficulties, and ethical dilemmas confronting researchers, practitioners, and healthcare managers in transitional bioinformatics. Results: The first results in translational medicine are appearing in the biomedical literature. All rely on bioinformatics methods for analysis. Conclusions: Translational medicine introduces new problems of interpretation and application to healthcare. Applying results to complex human-machine systems raises ethical issues, which are augmented in healthcare informatics. Bridging biological, medical, and informatics knowledge requires new epistemological approaches.

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